Shifaie is the best formulation for the glandular or endocrine system consists of the pituitary gland, sex glands, pancreas, hypothalamus and adrenal glands. Along with the nervous system, hormones, the secretion of the glands of the glandular system, are the major means of controlling the body's activities. The glandular system has a direct effect upon mood, mind, behaviour, immune defense, memory, control of metabolic rate, and all the glands depend upon one another and work together synergistically. The glandular system is necessary for survival; a healthy system is essential for health. An imbalance in any gland of the glandular system will cause enormous problems for the entire body. There are many problems that can happen because of the glandular imbalance. Vitamins, minerals and herbs nourish and restore glandular health.